According to Grimes none of the occupants of the home were injured in the fire, and CES crews rescued the pets on scene. Facebook0TwitterEmailPrintFriendly分享Central Emergency Services along with mutual aid from the Kenai Fire Department and Alaska State Troopers responded to a house fire off of Huntington Drive in Soldotna. This is a developing story- as of 4:30 p.m. crews were still on scene. Traffic on Huntington was blocked in both directions. CES Chief Dan Grimes: “We got called at 3:08 p.m., to report of a structure fire here off of Huntingdon. When we arrived we found heavy fire on the alpha side of the building, and coming from the roof. We went to work and made an aggressive interior attack starting putting the fire out.” CES responded with an engine, three medic units, and a mutual aid engine from Kenai. A total of 19 CES personal were on scene with two chiefs and a training officer.
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I don’t think so. And too, I wonder if all this “Web first” talk is just nonsense. When print makes up 50 percent to 75 percent of a typical magazine company’s revenue, can it possibly be “Web first in a fundamental way? The answer is no. No CEO is going to walk away from that kind of revenue in the interest of being Web first. So what’s really meant when companies say they’ve gone “Web first?” I think they’re trying to say they’ve gone “customer first.” I think they mean that the Internet has attributes that are so compelling and powerful that you’d be crazy not to make them the strategic core of your business.I think they want print to play a role that online-only companies only wish they could do too: To deliver impact, thought-leadership, stature, the final result and the critical ingredient of perspective, none of which are the Web’s strongest characteristics.I think print publishers recognize that in the marketing game, no one really thinks of himself as a lead, and that without the crucial steps early in the buying process of knowledge of a supplier, awareness of its message, trust in its solution and staying power, a lead is worthless. I’ve been reading a lot lately about media companies going “Web first.” I suppose it signals a recognition of the real-time value of Internet information, plus the invaluable online network of linkable relevant information, both inbound and outbound, plus the multidirectional conversations and communities the Web enables, plus the measurability of online marketing initiatives. I suppose it means that staff needs to be redeployed to serve online initiatives and businesses, and not be solely focused on print. I suppose that being “Web first” these days is better than being “print first.” But in a larger sense, what does “Web first” really mean? Does it mean we’re bound to evolve into online-only companies? Does it really mean that our print magazines are secondary? We’re ready, then, to walk away from the impact and power of the printed page, to consign it to a siding, a dead end, a vestigial appendage?
Toy Story 4, in theaters now, brings back familiar characters like Woody (Tom Hanks), Buzz Lightyear (Tim Allen) and Jessie (Joan Cusack) alongside new toys like Duke Caboom (Keanu Reeves), Forky (Tony Hale), Ducky (Keegan-Michael Key) and Bunny (Jordan Peele). Picking up where Toy Story 3 left off, Andy has passed his beloved toys to Bonnie, who’s getting ready to start kindergarten. She’s nervous about school, and Woody wants to help by tagging along, even though toys aren’t allowed. His decision ultimately leads the gang on a journey far from home as Woody does everything he can to keep Bonnie happy.Over the last two decades, advancements in Pixar’s animation tools have allowed it to create scenes and characters that wouldn’t have been possible in earlier films, such as Hank the octopus’ intricate movements in 2016’s Finding Dory and that opening rain scene in Toy Story 4. Still, Pixar has made sure to stay true to the look and feel of characters in each sequel. That’s no simple task. Because software evolves from movie to movie, filmmakers have to rebuild the characters every time.”If we try to use Toy Story 2 Woody, it’s like putting a CD-ROM into a Blu-ray player,” director Josh Cooley says. “It just wouldn’t work.”We’re introduced to new characters like Forky in Toy Story 4. Disney/Pixar After re-creating the characters, animators enhance them and add far more detail. In Toy Story 4, for example, they added fibers and weave to Woody’s clothing, and characters like Andy have a more smooth, realistic appearance. Filmmakers reference previous films to ensure visual consistency and check that characters animate the same way they always have. “We’ve created this world,” says production designer Bob Pauley. “We don’t want to mess with it.”Raising the barToy Story 4, which lands in US theaters June 21, opens with a flashback scene from nine years ago showing pouring rain outside Andy’s house. The incredibly realistic storm scene wouldn’t have been possible in earlier films, Pauley says. In fact, in the first Toy Story movie, filmmakers wanted to create a rainstorm in the scene where Woody and Buzz are trapped in Sid’s room. But they were limited by both the technology and experience on the team.So they came up with a compromise. Instead of showing pouring rain outside, they created shots showing rain dripping on the window from inside the bedroom. That way, they could more vaguely illustrate that it was raining outside without having to create the droplets.”It was every bit as emotional and important to the storytelling, but we just used a creative way to not have to do rain,” Pauley says.The antique shop features millions of objects. Disney/Pixar More advanced effects tools available today allowed Pixar to create realistic rain droplets in Toy Story 4’s opening sequence. Dust can also be added for atmosphere on floors, cabinets and rafters, and cobwebs add an ominous touch to darkened nooks and crannies. Shots of an antique mall were also an opportunity for Pixar to push its limits by creating millions of objects such as lamps, dishes and toys to create a realistic image of a crowded shop. 2 More Toy Story 1:49 Pixar’s Toy Story 4 brings new characters, cutting-edge… 2019 movies to geek out over Comments Now playing: Watch this: TV and Movies Tags Perhaps the biggest development since the first Toy Story is how images involving light are rendered. In the first film, creating a simple reflection off a mirror took about half a day to set up, says global technology supervisor Bill Reeves. Today, it’s essentially automated. A mirror simply has to be modeled with a reflective surface and tagged in the right way. Whereas before the work was in adding the reflections, the difficulty now lies in removing them if they’re distracting in a scene.Producer Jonas Rivera says they’ve pushed the bar on Toy Story 4, but they’ve also maintained visual consistency. “Our hope is that if you watched all [the movies] back to back, they would still have a continuity,” Rivera says. “You would definitely see the progression, but we worked hard in the art department in the way we shot the film to maintain that connectivity.”End of an era?Many critics and viewers thought Toy Story 3 was a perfect (albeit heartbreaking) ending to the film franchise. Which is why it came as a surprise to some people — including the filmmakers — that there would be a fourth installment. Enlarge ImageThe toys are back for another adventure — and maybe the last. Disney/Pixar “All of us have felt that each of these Toy Story movies were the end when they happened, so all of us are a little surprised even that we were making 4,” says producer Mark Nielsen. Still, Rivera, Nielsen and Cooley say this could in fact be the final Toy Story film. Even Tom Hanks, who voices Woody, has said Toy Story 4’s ending is “a moment in history.” (In other words: Get your tissues ready.) And, whatever it’s worth, he’s also said he could see there being a fifth film.”You never know,” Nielsen says. “But our focus has really been on making Toy Story 4 a complete film that falls in line with the others.” Share your voice Toy Story 4 review: Hilarious jokes barely save a story lacking stakes Toy Story 5 isn’t planned, but it ‘wouldn’t surprise’ star Tom Hanks Originally published June 18. Toy Story 4 hits theaters in the US on June 21. Disney/Pixar In 1995, when Pixar released Toy Story, the first feature-length computer animated film, the studio pushed the limits of what was possible when it illustrated rain with smudges on a window rather than individual droplets. Fast forward 24 years to Toy Story 4, and viewers will see a remarkably life-like, detailed storm that shows the impact of raindrops on objects and water gushing in the street. Pixar’s technology has come a long way in two decades. 77 Photos Pixar
Share Wikipedia Commons / Flickr / Ed SchipulDarian Ward, press secretary for Houston Mayor Sylvester Turner, was recently suspended without pay for 10 days because she didn’t properly respond to an inquiry based on the Texas Public Information Act (TPIA) regarding a personal business.Darian Ward, press secretary for Houston Mayor Sylvester Turner, was recently suspended without pay for 10 days because she didn’t properly respond to an inquiry based on the Texas Public Information Act (TPIA) regarding a personal business.According to an official letter signed by Turner and sent to Ward on December 11th by Alan Bernstein, the mayor’s director of communications, the press secretary didn’t produce accurate information about emails she wrote using her City email account in regards to activities related to the work of the production company Joy in Motion.The letter states that, back in November of 2017, Ward notified Bernstein and Marvalette Hunter, Turner’s chief of staff, she responded to the inquiry, which came from a Houston based reporter, with 30 pages.However, an email system search conducted by the City’s Office of Inspector General found approximately 5,000 emails related to Joy in Motion, as well as other personal and non-City business matters, over the period going from February of 2014 to October of 2017.“Ms. Ward, you misrepresented to the requester the volume of documents regarding the TPIA request under state law, and you misinformed the Chief of Staff and me; you spent a significant amount of city time conducting your personal business rather than focusing on your work task,” Bernstein asserted in his letter to Ward, who was suspended from December 12th to December 27th of 2017 for violating City of Houston policies regarding outside employment and the use of information technology resources.According to the letter, Ward also used her City account to send emails related to a charity organization that has no affiliation with the City of Houston.On Wednesday, Mayor Turner said during his customary media availability held after the Council meeting that the City’s Legal and Human Resources departments analyzed the situation and he went “over and above the recommendation that was handed to me.”Ward has been employed by the City of Houston since October 6th 2008.
The AFRO social columnist has been an integral part in the newspaper’s success since it’s rise to dominance in the 1930’s, and the social columnist still plays an important role in the AFRO’s pages in 2019. For more than a decade Valerie Fraling, author of “Living For the Weekend,” has continued that tradition. Recently, Fraling made the decision to step away as an AFRO columnist after more than 10 years.AFRO social columnist Valerie Fraling. (Courtesy Photo)“It’s (society column) always been a very important category for the AFRO readership. Val stepped in and filled that void,” said John “Jake” Oliver, AFRO Publisher Emeritus. “She provided the content and provided the news…she’ll be sorely missed,” Oliver added. The AFRO wishes Valarie Fraling all the best in her future endeavors.
The two-time All-ACC selection currently leads the Cardinals with a 72.3 stroke average for the 2018-19 season. Hartlage tallied top 10 showings in three of five tournaments and closed out the fall with a runner-up finish at the Alexa Stirling Intercollegiate. She opened the spring season with a win in the Moon Golf Invitational. Hartlage will begin second round play on Thursday morning on the 10th tee at 10:00 a.m. Print Friendly Version Story Links AUGUSTA, Ga. – University of Louisville junior Lauren Hartlage is tied for 40th after first round play in the inaugural Augusta National Women’s Amateur Championship on Wednesday afternoon. The Elizabethtown, Ky. native was able to settle down after the first five holes and par 10 out of the 11 remaining holes. She eagled the par-4 seventh hole. She finished just one over on the back nine to move up in the rankings throughout the day. On the day, Hartlage shot a 76 to finish four over. The first two rounds, April 3-4 are played on the Island and Bluff nines at Champions Retreat Golf Club in Augusta. The entire field will then play Augusta National for an official practice round April 5. The final 18 holes will take place at Augusta National on April 6 and will feature the top 30 competitors who made the cut.NBC Sports will produce and broadcast three hours of live final-round coverage at Augusta National from Noon – 3 p.m. EDT on April 6, 2019. NBC Sports will also provide pre-event promotion across NBCUniversal’s portfolio, while Golf Channel will deliver highlights, live reports and news coverage throughout the event, including onsite during the first two competitive rounds at Champions Retreat. Additionally, Golf Channel’s “Live From the Masters” will commence on Friday, April 5 from Augusta National and wrap ANWA coverage on Saturday, April 6 and the Drive, Chip and Putt National Finals on Sunday, April 7.
×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15 Michelle Obama’s “Becoming” was first released Nov. 13, 2018, by Penguin Random House’s Crown Publishing, and is being published in 44 languages around the world. The book was a No. 1 New York Times bestseller after one week of sales, and to date has sold more than 5.9 million units in all formats and editions in the U.S. and Canada.Separately, Barack and Michelle Obama have established a production company, Higher Ground Productions, which has a multiyear development deal with Netflix. On Tuesday, Higher Ground named Priya Swaminathan, formerly with Annapurna, and Tonia Davis, who hails from Chernin Entertainment, as co-heads of the venture.The “BookTube” special featuring Michelle Obama comes from the YouTube Originals group, led by global head of original content Susanne Daniels.Last fall, YouTube switched up its strategy on original productions to what it calls “Single Slate,” under which it will make all of its originals available on a free, ad-supported basis — signaling a move toward projects with broad, mainstream appeal rather than those built around YouTube personalities. In many cases, YouTube will window series and movies to premiere first on the YouTube Premium subscription service before making them available for free. YouTube has tapped Michelle Obama to headline an original special, “BookTube,” slated to debut next month during Women’s History Month.The former First Lady will discuss her bestselling memoir “Becoming” with a panel of YouTubers. John Green — best-selling author of books including “The Fault in Our Stars” and co-founder of YouTube channels vlogbrothers and Crash Course — will moderate the discussion. Along with Michelle Obama, the special will feature a panel of YouTube creators including Jouelzy, Ariel Bissett, Kat O’Keeffe, Jesse George and Franchesca Ramsey.YouTube plans to release the original special in March, to be available for free, with an exact date yet to be determined. “BookTube” will comprise seven short-form “chapters,” each under 10 minutes, based on the questions from the YouTube creators for Michelle Obama. Popular on Variety
Popular on Variety India’s digital-only platforms are witnessing rapid growth — 262% in 2018 according to a recent EY report — and Indians are increasingly consuming content on mobile devices, thanks to cheap data plans. Netflix is testing a $3.63 per month, half its current basic plan, with selected subscribers in India.The company’s slate of Indian original content has grown to 11 series and 22 films. The next Indian original is Deepa Mehta’s “Leila” that streams from June 14. ×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15 Industry veteran Monika Shergill has been hired by Netflix as it new head of series and international originals with a focus on India.Shergill was previously executive VP and head of content at Viacom 18 Digital Ventures from 2015, where she was responsible for launching several multi-lingual series on its Voot streaming service. Previously, she held key positions at Star India, where she served from 2007, and prior to that at Sony Entertainment Television from 2002.Shergill will replace Simran Sethi, who declined to move from Los Angeles to India for personal reasons. Earlier, another high-profile Netflix executive, Swati Shetty, chose not to move back to Mumbai from Los Angeles, and instead joined Brian Grazer and Ron Howard’s Imagine Entertainment as EVP, international content, a Los Angeles-based position.
LaVar Ball once claimed he could beat Michael Jordan and LeBron James in a game of one-on-one, but a viral video of him actively sucking it up in an old rec league game got him laughed at by everyone with an internet connection. Now there’s some new footage, albeit brief, of LaVar showing off his “game” in a parking lot one-on-one duel with Lonzo’s manager Darren Moore, and it’s not pretty either. In the short clip, LaVar does actually make a deep jumper, but he also flips up a weak, awkward post up that will give you a laugh. If he has trouble taking down Darren Moore, it’s tough to see him handing his Airness an L.
4 min read Growing a business sometimes requires thinking outside the box. For small businesses, the new millennium has arrived about a decade late. The big year for innovation was supposed to be 2001, when things like artificial intelligence and a worldwide-networked office were said to be to coming to market. But it has taken an extra 10 years of digital toiling to make some of these tools a reality.In 2011, small-business owners will face a staggering array of new technologies and services. These won’t be for-geeks-only stuff. These are mainstream business systems from the tech giants — tools you may want to consider adopting or you could get left behind.Here are my thoughts on the top business technology trends for 2011. You’ll need to be familiar with these if you want to stay on the cutting edge of your market.1. The Web on your phone might be as fast the Web in your office. The biggest game-changing tool for 2011 is a new generation of fast wireless cellular standards known as 4G. By midyear, most mobile consumers will be able to receive service that’s similar to the robust, plugged-in Web access found in an office. All the major phone carriers will be offering it, including Verizon Communications Inc., Sprint Nextel Corp., AT&T Inc. and T-Mobile USA Inc. Look also for offerings from start-ups, such as Antelecom Inc., Clearwire Corp., Xanadoo Co. and Towerstream Corp., and from cable companies like Comcast Corp. and Time Warner Cable Inc.However, coverage is likely to be spotty and comparing plans could be a struggle, at least in the early days. The cost may be as high as $60 a month per employee and sharing a Web connection won’t be an option. But those willing to brave the trials of moving to a technology early may not only be able to say goodbye to their existing data provider but they may never again need a hard-wired Web connection. The mobile business race really begins in 2011.2. Day planners won’t just track your schedule. Starting next year, smart Web-based business-automation tools will find their way into business software and begin offering opinions on everything from how you should manage tasks to how you arrange meetings and budget projects. Already, Google is adding a sophisticated feature to its Gmail Priority Inbox email services that is designed to help users sort emails in order of their importance. Companies such as Intuit Inc. are adding financial modeling tools to QuickBooks and Mint.com that are so sophisticated that they can guess when you will lose money.Startups are also offering tools to help firms write documents and create content. The leader now is StatSheet Inc., a Durham, N.C.-based technology company that specializes in sports content. In October, it introduced a Web-based service that automatically creates legible articles, analysis and data with nearly no direct human involvement. What does that mean to you? For better or worse, you may soon face the daunting prospect of managing memos and business correspondence that, in some ways, write themselves.3. Work life might be controlled by the touch of a finger. Call it the iPhone effect for businesses. A new generation of Apple Inc.’s iPad-inspired, touch-controlled work tools will go mainstream in 2011.A range of office standbys from printers to desktop PCs will add iPhone-like touch-pad controls. A slew of touch-enabled kiosks, displays and machine controls will be cheap and widely available.The effects are likely to be profound. Touch-enabled screens, just like on iPhones, will allow for a wide swath of new features and functions to be built into just about any business device. Printers will not only connect to the Web but will also produce custom news feeds. Touch-enabled PCs will support both traditional office software and sophisticated inventory and business-management tools that once required pricey custom hardware.Aggressive first movers are already making an impact. For example, San Francisco-based Touch Revolution is developing a line of mobile-phone savvy touch-enabled control modules that are being adapted to everything to office systems to kitchen appliances.By this time next year, your fingers may not only do the walking around the office. They may do the talking as well. Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global Opinions expressed by Entrepreneur contributors are their own. Register Now » December 29, 2010
Posted by Thursday, September 13, 2018 Share Travelweek Group How perceptive is Canada compared to other countries? Take the quiz here TORONTO — Way to go, Canada! We’re not as ignorant as other countries of the world.According to a new survey from Ipsos MORI, Canada ranks 32nd in The Perils of Perception 2017 survey. The good news? The United States fared even worse in 23rd place.The study, says Ipsos, highlights how wrong the online public across 38 countries are about key global issues and features of the population in their home country. A total of 29,133 interviews were conducted between Sept. 28-Oct. 19, 2017 via the Ipsos Online Panel system.“Across all 38 countries in the study, each population gets a lot wrong,” said Bobby Duffy, Managing Director of Ipsos MORI Social Research Institute, London. “We are often most incorrect on factors that are widely discussed in the media, such as deaths from terrorism, murder rates, immigration and teenage pregnancy.”Duffy added that there are multiple reasons for these errors, “from our struggle with maths and proportions, to media and political coverage of issues, to social psychology explanations of our mental shortcuts or biases.” But based on previous studies, he added, “this is partly because we overestimate what we worry about: the more we see coverage of an issue, the more prevalent we thing it is, especially if that coverage is frightening or threatening.”More news: Can you guess the one and only hotel company to rank on Indeed’s Top Workplaces in Canada list?South Africa received the dubious honour of being the most inaccurate in their perceptions, with Brazil and the Philippines rounding out the top three.Here is the complete list:South AfricaBrazilThe PhilippinesPeruIndiaIndonesiaColombiaMexicoTurkeySaudi ArabiaArgentinaItalyChileJapanMalaysiaFranceSouth KoreaHungaryNew ZealandNetherlandsHong KongPolandUnited States of AmericaRussiaGermanyAustraliaChinaSingaporeIsraelGreat BritainBelgiumCanadaSerbiaMontenegroSpainDenmarkNorwaySwedenHow well do you think you know your stuff about Canada’s top issues? Take the Ipsos quiz here: http://perils.ipsos.com/quiz/index.html Tags: IPSOS, Statistics << Previous PostNext Post >>
A 40.8% increase in American tourists, a 95% increase in visitor nights by Germans, and continued growth in the New Zealand market saw the Sunshine Coast record a 7.1% increase in international visitor nights to 2.9 million visitor nights in the year ending March 2016.The VS) statistics from Tourism Research Australia also revealed that holiday nights spent on the Sunshine Coast were up 29% to 1.6 million, and average length of stay increased 24.2% to 7.7 nights per visit.International tourism expenditure increased 17.8% to $236 million, close to the highpoint in international expenditure reached in March 2010.A feature of the latest IVS figures was the growth in the American market. With the ‘Bindi factor’ (the success of Bindi Irwin in America’s Dancing with the Stars) reaching a crescendo in late 2015, the spotlight on the Sunshine Coast translated into a growth rate in US visitors of 40.8%, compared to the Queensland average growth rate of 19% for the same period.“The massive increase in international visitor nights and expenditure is a result of our targeted activity in the traditionally long-stay and high-yield American and European markets over the past year,” said acting CEO of Visit Sunshine Coast, Simon Latchford.“Bindi Irwin’s high profile success in Dancing with the Stars and her focus on her Sunshine Coast home and Australia Zoo have created a very positive image for the region, and our marketing campaigns in Germany have been equally effective.“By focusing on the diversity of activities available to visitors we have managed to substantially increase the length of stay and the resulting expenditure.“With the green light given for expansion of Sunshine Coast Airport and with Brisbane Airport attracting new international flights from North America and Asia, we are very optimistic about our growth prospects in both the shorter and longer terms, especially with the rapidly growing demand for nature tourism in our key source markets.” Visit Sunshine Coast Source = Visit Sunshine Coast
Categories: Filler News 05Mar Rep. Filler says focus should be on lowering car insurance rates, not raising gas taxes State Rep. Graham Filler of DeWitt today issued the following statement after Gov. Gretchen Whitmer announced her state budget proposal:“Michigan is No. 1 for all wrong reasons when it comes to the cost of driving, and the governor’s proposed 45-cent per gallon gas tax increase would make things even worse. It would force Michigan drivers to pay the highest gas taxes in the United States – and that’s not something we want to be known for.“Michigan drivers already pay the highest car insurance rates in the nation. Let’s work on lowering these rates first – before there’s any talk of asking drivers to pay even more at the pump.”###
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Two groups have been chosen to set up new centres for independent living (CIL) in Wales, doubling the number of CILs in the country.The new centres will be located in Ceredigion, in the west of the country, and Flintshire, in the north, and will both be run and controlled by disabled people.Although there are only two existing CILs in Wales, the long-term aim is to have one in every one of its 22 counties.The two new CILs were selected by Disability Wales, the Wales Co-operative Centre (WCC), and Dewis Centre for Independent Living, as part of the £318,000 Welsh government-funded Enabling Wales programme.Disability Wales said it hoped they would provide “a kick start to developing more CILs across Wales”.The two groups will now receive support from Disability Wales, WCC and Dewis CIL as they work towards opening their doors to disabled people next March.That support will include help with the bids they will need to make to local authorities, the Welsh government and other sources of funding to allow them to meet their running costs.Disability Wales said the two groups would need to “strike a balance between their traditional campaigning role… with the need to operate successfully within a highly competitive commercial environment, and to manage the potential conflicts of interest when delivering public contracts”.The Ceredigion CIL will focus on providing information and advice – including disability equality training; self-advocacy; offering support to victims of hate crime; campaigning; and fundraising – and will be run by the disabled people’s organisation Disabled People Together, as well as the non-user-led groups Mencap Ceredigion and Creative Lifestyle Solutions.Rhiannon Hicks, Enabling Wales project officer at Disability Wales, said: “The Ceredigion group were successful as they showed a strong understanding of organisations led by disabled people for disabled people.“They also have a strong commitment to the social model of disability, as well as good partnerships with relevant third sector bodies.”The Flintshire CIL will be run by the user-led Flintshire Disability Forum (FDF), and will provide services such as help with managing personal budgets; campaigning; recruitment and training of personal assistants; assistance completing application forms; and equipment hire.Hicks said: “The FDF were successful as they have a strong track record of project delivery, and of securing funding. They also have strong partnerships.”She added: “I very much look forward to working with both groups in the next stage of the project.”Rhian Davies (pictured), director of Disability Wales, said: “We are delighted that following an 18-month long programme of training, development and coaching, working with 65 disabled people across Wales, we have achieved our goal in being able to select two emerging CILs and support their development over the remainder of the Enabling Wales project.“CILs are social enterprises that deliver services run by disabled people for disabled people and offer a new and creative model of provision in line with what people actually need to achieve independent living and well-being as well as maximise scarce resources.”Disability Wales said it hoped the new organisations would in time be able to support other groups towards becoming CILs, while it would itself be providing a “tool kit” on how to set up a CIL.Carl Sargeant, the Welsh government’s cabinet secretary for communities and children, congratulated the two groups, and said: “I am sure that, with the support of the Wales Cooperative Centre and Dewis CIL, they will develop and grow into sustainable enterprises which will promote independent living for disabled people and provide them with the services they need to support their well-being.”Picture by Natasha Hirst
OOH Advertising Solution Provider Quorum Leverages Quadrants Filtered Authenticated Location Data to
Marketing Technology NewsNewsOOH advertisingout-of-home advertising solutionQuadrantQuorum Previous ArticlePFL Hosts Ribbon Cutting Ceremony to Celebrate New Digital Production & Fulfillment CenterNext ArticleAtento Opens a New Customer Relationship Center in Madrid Quadrant’s High Volume Location Data Sets Stamped with Blockchain-Enabled Authentication Technology Giving Quorum Unprecedented ‘Hyperlocal’ Targeting Ability Throughout Entire Consumer Journey Quadrant, the platform that maps and authenticates data making it easier to buy and sell quality, authentic data feeds, announced that it is providing out-of-home (OOH) advertising solution provider Quorum with authenticated, filtered location data to accurately target the consumer in motion. Quadrant supplies Quorum with location data that is accurate, at scale and contains the right type of data, strengthening Quorum’s ability to execute, link, measure and analyse OOH advertising to wider marketing campaigns.Quadrant’s high-volume location data, which includes time, date, location and anonymous ID’s of consumer mobile devices, is stamped with blockchain-enabled data authentication technology ensuring accuracy as at the time of stamping. This data, which originates from multiple sources, is filtered to ensure that only the most relevant points are delivered to Quorum, who in turn processes it through its own algorithm to identify consumers who have passed specific billboards and visited other specific Points of Interest (POI). By integrating this level of precise, authentic location data, Quorum enables advertisers to more deeply understand the customer journey – to and from where they are travelling and when – and to target those consumers with a more strategic and customized approach. Marketing Technology News: New ISG Study Focuses on Digital Business Services“Quadrant’s data allows Quorum to offer much more relevant and accurate targeting solutions for its clients” says Mike Davie, CEO of Quadrant. “Quadrant’s Data as a Service (DaaS) model makes it easier for Quorum to find and use large location data sets. This allows advertisers to plan and execute mobile companion advertising campaigns in coordination with their outdoor programs, giving them accuracy at a lower cost, and therefore better ROI.”Marketing Technology News: ada Strengthens Its Leadership Team as It Doubles Its Headcount“We deliver a ‘one-two’ effect for clients who want to follow up on the awareness generated by a billboard or other outdoor placement with a response-focused mobile advertisement, and a new form of analytics that converges data points from both the outdoor and mobile media channels,” says Ezra Doty, CEO and Co-Founder at Quorum. “By tapping Quadrant’s refined location data, Quorum is able to expand its platform’s reach and accuracy. The filtered data that Quadrant provides is well suited for our needs and allows us to feed it into our own algorithms to generate highly accurate results.”Marketing Technology News: SeQuel Response Hires New Director of Marketing to Propel Brand Awareness OOH Advertising Solution Provider Quorum Leverages Quadrant’s Filtered, Authenticated Location Data to Reach Consumer in Motion with Accuracy and Scalability MTS Staff Writer6 days agoJuly 12, 2019
Reviewed by James Ives, M.Psych. (Editor)Apr 4 2019Gene editing has been a much sought after and controversial technology. Last month, part of the World Health Organization called for an international registry to track all research into editing the human genome.Purdue University researchers, including one who was inspired by the cancer death of a close friend, have developed a new technology that could change how gene editing is approached in the future. The research team presents the work on April 4 at the National Meeting of the American Chemical Society in Orlando.One of the most widely used methods for gene editing is CRISPR-Cas9 technology. The method requires a certain sequence or motif for function that restricts modifications.”CRISPR can be programmed to cut DNA at specific regions to make precise edits in an organism that can increase sustainable manufacturing, treat disease and even create better crops,” said Kevin Solomon, an assistant professor of agricultural and biological engineering, who leads the Purdue research team. “However, it requires a certain sequence for function that restricts modifications to certain regions.”Related StoriesMother calls for protein shake regulation after daughter diesEMBL study reveals uncoupling between chromatin topology and gene expressionResearchers discover gene linked to healthy aging in wormsMany diseases in humans, including several types of cancer, are caused by mutations at specific sites in the genome. The Purdue team created a method that uses the protein Argonaute from Natronobacterium gregoryi (NgAgo) and supplied DNA as a guide to enable modification anywhere on the genome, providing new options to potentially improve manufacturing, disease treatment, drug discovery and crop production.”While there is still work to do, we have shown that these molecular scissors can edit regions of DNA previously inaccessible by current technologies,” said 2nd Lt. Michael Mechikoff, a master’s student working on the project.”One of my best friends died from a cancer caused by a genetic variant several years ago,” said Kok Zhi Lee, a doctoral student who works on the research team in Solomon’s lab. “I always dreamed of a different scenario for my friend – living in an era where genetic engineering is a regular and safe option to correct genetic disorders. With the potential of our technology, I anticipate a future where genetic disease is history for human beings.”The team has worked with the Purdue Research Foundation Office of Technology Commercialization to file a utility patent on the technology. They are looking for partners and others interested in developing and licensing it.Their work aligns with Purdue’s Giant Leaps celebration, acknowledging the university’s global advancements in health as part of Purdue’s 150th anniversary. It is one of the four themes of the yearlong celebration’s Ideas Festival, designed to showcase Purdue as an intellectual center solving real-world issues.Source: https://www.purdue.edu/
Reviewed by Alina Shrourou, B.Sc. (Editor)Jun 23 2019The U.S. Food and Drug Administration today approved Vyleesi (bremelanotide) to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. There are women who, for no known reason, have reduced sexual desire that causes marked distress, and who can benefit from safe and effective pharmacologic treatment. Today’s approval provides women with another treatment option for this condition. As part of the FDA’s commitment to protect and advance the health of women, we’ll continue to support the development of safe and effective treatments for female sexual dysfunction.”Hylton V. Joffe, M.D., M.M.Sc., director of the Center for Drug Evaluation and Research’s Division of Bone, Reproductive and Urologic Products HSDD is characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to a co-existing medical or psychiatric condition, problems within the relationship or the effects of a medication or other drug substance. Acquired HSDD develops in a patient who previously experienced no problems with sexual desire. Generalized HSDD refers to HSDD that occurs regardless of the type of sexual activity, situation or partner.Vyleesi activates melanocortin receptors, but the mechanism by which it improves sexual desire and related distress is unknown. Patients inject Vyleesi under the skin of the abdomen or thigh at least 45 minutes before anticipated sexual activity and may decide the optimal time to use Vyleesi based on how they experience the duration of benefit and any side effects, such as nausea. Patients should not use more than one dose within 24 hours or more than eight doses per month. Patients should discontinue treatment after eight weeks if they do not report an improvement in sexual desire and associated distress.The effectiveness and safety of Vyleesi were studied in two 24-week, randomized, double-blind, placebo-controlled trials in 1,247 premenopausal women with acquired, generalized HSDD. Most patients used Vyleesi two or three times per month and no more than once a week. In these trials, about 25% of patients treated with Vyleesi had an increase of 1.2 or more in their sexual desire score (scored on a range of 1.2 to 6.0, with higher scores indicating greater sexual desire) compared to about 17% of those who took placebo. Additionally, about 35% of the patients treated with Vyleesi had a decrease of one or more in their distress score (scored on a range of zero to four, with higher scores indicating greater distress from low sexual desire) compared to about 31% of those who took placebo. There was no difference between treatment groups in the change from the start of the study to end of the study in the number of satisfying sexual events. Vyleesi does not enhance sexual performance.Related StoriesTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTSchwann cells capable of generating protective myelin over nerves finds researchLipid-lowering drugs are underutilized for preventing atherosclerotic cardiovascular diseaseThe most common side effects of Vyleesi are nausea and vomiting, flushing, injection site reactions and headache. About 40% of patients in the clinical trials experienced nausea, most commonly with the first Vyleesi injection, and 13% needed medications for the treatment of nausea. About 1% of patients treated with Vyleesi in the clinical trials reported darkening of the gums and parts of the skin, including the face and breasts, which did not go away in about half the patients after stopping treatment. Patients with dark skin were more likely to develop this side effect.In the clinical trials, Vyleesi increased blood pressure after dosing, which usually resolved within 12 hours. Because of this effect, Vyleesi should not be used in patients with high blood pressure that is uncontrolled or in those with known cardiovascular disease. Vyleesi is also not recommended in patients at high risk for cardiovascular disease.When naltrexone is taken by mouth, Vyleesi may significantly decrease the levels of naltrexone in the blood. Patients who take a naltrexone-containing medication by mouth to treat alcohol or opioid dependence should not use Vyleesi because it could lead to naltrexone treatment failure.In 2012, the FDA identified female sexual dysfunction as one of 20 disease areas of high priority and focused attention. The FDA held a two-day meeting in October 2014 to advance the agency’s understanding of female sexual dysfunction. During the first day of the meeting, the FDA solicited perspectives directly from patients about their condition and its impact on daily life. In 2016, the FDA published a draft guidance titled “Low Sexual Interest Desire and/or Arousal in Women: Developing Drugs for Treatment,” to assist companies developing drugs for the treatment of these conditions. The FDA is committed to continuing to work with companies to develop safe and effective treatments for female sexual dysfunction.The FDA granted approval of Vyleesi to AMAG Pharmaceuticals. Source:U.S. Food and Drug Administration
15 Amazing Images of Stars There’s a rebellious, half-dead star in the Little Dipper that’s hellbent on escaping our galaxy — and now, astronomers have an idea why. The star, a small white dwarf that’s moving incredibly fast toward the edge of the galaxy, may be one of just a handful of known white dwarfs that exploded in supernovas and lived to tell the tale, according to a study published June 21 in the journal Monthly Notices of the Royal Academic Astronomical Society. The study authors said this unusual star, named LP 40−365, is a “partly burnt runaway remnant,” suggesting that a peculiar, weaker-than-average supernova rendered the star much smaller, faster and toastier than a typical white dwarf. Strange as it appears, this stellar oddity may not be alone; using data from the European Space Agency’s Gaia space telescope, the study authors also found three additional stars in other parts of the galaxy with properties and trajectories similar to LP 40-365’s.Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65914-partly-burnt-remnants-survive-supernova.html?jwsource=cl已复制直播00:0000:3500:35 The researchers said these four oddball stars may represent a newfound type of fate for white dwarfs that run out of fuel and explode — a fate that leaves them charred, shrunken and streaking across the galaxy at incredible velocities, but still largely intact. These partly burnt dwarfs “form a distinct class of chemically peculiar runaway stars,” the study authors wrote, and the objects could shed their own weird form of light on the complex factors that cause stars to explode in the first place. A modest thermonuclear explosion When a large star exhausts all of its nuclear fuel, it may shed its outer layers of matter and shrink into a hot, shriveled husk called a white dwarf. Eventually, as gravity continues compacting that dying star core, the star may collapse, explode in a supernova, and leave behind an ultradense neutron star or black hole. The authors of the new study said stars like LP 40−365 represent a third possible fate for exploded dwarfs. To meet this fate, the white dwarf must explode in a peculiar, theoretical sort of explosion called a type Iax supernova. Essentially, previous studies have argued, these are smaller-than-average supernovas capable of ripping away some of a white dwarf’s matter while leaving its core largely intact. In addition to blowing away a bunch of the afflicted star’s mass, a type Iax supernova may kick that star out of its orbit — possibly sending the star flying so fast that it is no longer bound by the gravitational pull of its home galaxy. Stars like LP 40−365 will almost assuredly escape into intergalactic space in time, the authors wrote, and satellite images already show this happening. (Take a look at these two images of LP 40−365, taken in 1955 and 1995, to see how its escape is already warping the shape of the Little Dipper.) It’s not unusual for a renegade star to get punted across the universe after, say, its binary partner explodes or gets sucked into a black hole. But it’s quite another matter for an old star to collapse into a white dwarf, explode in a supernova and then keep on smoldering as an even-smaller white dwarf. Besides their impressive speed (they move at hundreds of miles per second), partly burnt remnants are also unusual for their size; they are much smaller than a typical white dwarf, having lost much of their mass in the supernova. They also retain clear traces of past supernovae in their atmospheres, which are rich in ash and heavy elements but lacking in light elements like hydrogen and helium, which may have burnt away. The researchers said they are optimistic that, by looking for these telltale features, the Gaia satellite could detect as many as 20 additional partly burnt stellar remnants before the instrument’s mission ends in 2022. That could provide enough evidence to prove that some stars have what it takes to survive a supernova explosion, even if the experience leaves them eager to find a new galactic home. 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